Factors to consider when purchasing a freeze dryer

1. Manufacturer selection.

It is preferred to have a powerful freeze dryer factory, and has many years of professional experience in the production of freeze dryer and professional technology, support non-standard, solutions.

2. Cold trap temperature.

A cold trap is a device used to trap steam between a freeze-drying chamber and a vacuum pump. The lower the cold trap temperature is, the stronger the capture capability of the cold trap is, but the cold trap temperature is low, the higher the refrigeration requirement is, and the machine cost and operating cost are relatively high.

Shanghai Tian Feng laboratory cold trap temperature of the freeze dryer mainly - 50 ℃, 60 ℃, 80 ℃ 3 class. Cold trap temperature was 50 ℃ of freeze drying machine is suitable for the water solvent or solvent in freeze-dried products more than 40 ℃, freezing point temperature of cold trap capture water ability experiments show that the influence of the temperature of cold trap decreased from - 35 ℃ to - 50 ℃, water ability improve obviously, cold trap temperature below - 50 ℃, cold trap catching capacity of ascension is not obvious. Therefore, in the case of no special requirements, choose cold trap temperature - 50 ℃. Cold trap temperature to - 80 ℃ or so of freeze drying machine is suitable for most of the products such as freeze-drying product with organic solvent or some special products of freeze-dried.

3. Amount of condensation.

The amount of steam trapped in a cold trap is related to the amount of water or other solvents sublimated in the laboratory's daily experimental samples. The volume of cold well ice condensation in the freezing dryer of Shanghai tianfeng laboratory is 3kg, 6kg and 8kg, which is suitable for various experimental requirements.

4. Ultimate vacuum

The ultimate vacuum reflects the leakage of the freeze dryer and the efficiency of the vacuum pump. The vacuum degree of the experimental operation should be within a reasonable range. The vacuum degree is too high, which is not conducive to heat transfer.

5. Control the display system

Laboratory series of freeze - drying machines, mainly used in material freeze-drying, small - batch production and freeze-drying process conditions test. The control system should have real-time display of parameters of freeze-drying process, such as cold well temperature, vacuum degree, stage time and total process time. Establish, modify and effectively implement the lyophilization process; It is better to have communication interface for data collection and storage. Shanghai tianfeng laboratory refrigeration dryer series adopt PID controller, suitable for different experimental requirements.

6. Freeze-drying method and function.

According to the specific samples, the freeze-drying method is also different. The common freeze-drying experiment in the laboratory is Process B, that is, freeze-drying in the freeze-drying chamber or freeze-drying in the hanging bottle. If freeze-drying chamber is freeze-drying, the freeze-drying chamber shall be selected, and the freeze-drying chamber shall be selected. If the hanging bottle is freeze-dried, the multi-manifolds should be selected, which are suitable for round bottom flask, wide mouth filter bottle or ampoule bottle. However, it should be noted whether the corresponding adapter should be selected for combined use. If the samples involved in the user's test are both freeze-dried in the cavity and freeze-dried in the hanging bottle, the freeze-dried cavity with the external outlet can be selected.

Different experiments and different samples have different functional requirements for the freeze-drying machine. Generally speaking, it is recommended to use shelf freeze-drying machine for the freeze-drying of food, Chinese herbs, powder materials and other samples. For cylinder operation, it is necessary to choose a freeze dryer with cover device. The freeze-drying preservation of microbial strains is suggested to adopt bottle hanging type and must choose ampoule bottle adapter for freeze-drying. If you want to study the freeze-drying process curve, you must choose the type of machine whose controller can support the work of eutectic point test device and software.